Condensed Consolidated Balance Sheets (unaudited) - USD ($) $ in Thousands	Sep. 30, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 66,478	$ 161,160
Marketable securities	73,155	138,343
Prepaid expenses	8,270	25,628
Receivables and other current assets	12,535	11,389
Total current assets	160,438	336,520
Marketable securities	1,407	97,114
Property, plant and equipment, net	11,535	9,706
Goodwill	5,646	5,646
Operating lease right-of-use assets	288,684	91,532
Restricted cash and other non-current assets	52,388	53,277
Total assets	520,098	593,795
Current liabilities:
Accounts payable	18,622	25,883
Accrued expenses and other current liabilities	64,314	103,958
Operating lease liability, current portion	43,791	23,152
Total current liabilities	126,727	152,993
Operating lease liability, net of current portion	234,422	66,432
Other non-current liabilities	92	93
Total liabilities	361,241	219,518
Commitments and contingencies (Note 9)
Stockholders’ equity:
Preferred stock, $0.01 par value, 5,000 shares authorized; 0 shares issued and outstanding at September 30, 2022 and December 31, 2021	0	0
Common stock, $0.01 par value, 125,000 shares authorized; 82,880 and 71,115 shares issued and outstanding at September 30, 2022 and December 31, 2021, respectively	829	711
Additional paid-in capital	4,181,393	4,096,402
Accumulated other comprehensive loss	(4,630)	(2,911)
Accumulated deficit	(4,018,735)	(3,719,925)
Total stockholders’ equity	158,857	374,277
Total liabilities and stockholders’ equity	$ 520,098	$ 593,795