Condensed Consolidated Statements of Operations and Comprehensive Loss (unaudited) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
Revenue:
Total revenues	$ 1,519	$ 143	$ 3,464	$ 1,037
Operating expenses:
Research and development	63,841	84,645	141,716	167,488
Selling, general and administrative	36,694	54,984	72,800	118,553
Cost of product revenue	1,745	15,215	10,055	15,791
Restructuring expenses	6,639	0	6,639	0
Total operating expenses	108,919	154,844	231,210	301,832
Loss from operations	(107,400)	(154,701)	(227,746)	(300,795)
Interest income, net	174	218	280	573
Other (expense) income, net	7,088	(1,274)	5,176	23,027
Loss before income taxes	(100,138)	(155,757)	(222,290)	(277,195)
Income tax (expense) benefit	0	(216)	0	(282)
Net loss from continuing operations	(100,138)	(155,973)	(222,290)	(277,477)
Net loss from discontinued operations	0	(85,729)	0	(170,033)
Net loss	$ (100,138)	$ (241,702)	$ (222,290)	$ (447,510)
Net loss per share from continuing operations - basic (in dollars per share)	$ (1.36)	$ (2.31)	$ (3.02)	$ (4.13)
Net loss per share from continuing operations - diluted (in dollars per share)	(1.36)	(2.31)	(3.02)	(4.13)
Net loss per share from discontinued operations - basic (in dollars per share)	0	(1.27)	0	(2.53)
Net loss per share from discontinued operations - diluted (in dollars per share)	0	(1.27)	0	(2.53)
Net loss per share - basic (in dollars per share)	(1.36)	(3.58)	(3.02)	(6.66)
Net loss per share - diluted (in dollars per share)	$ (1.36)	$ (3.58)	$ (3.02)	$ (6.66)
Weighted-average number of common shares used in computing net loss per share - basic (in shares)	73,767	67,487	73,727	67,233
Weighted-average number of common shares used in computing net loss per share - diluted (in shares)	73,767	67,487	73,727	67,233
Other comprehensive (loss) income:
Other comprehensive income	$ 43	$ (328)	$ (1,505)	$ (272)
Comprehensive loss	(100,095)	(242,030)	(223,795)	(447,782)
Product revenue
Revenue:
Revenue	1,331	0	2,739	724
Other revenue
Revenue:
Revenue	$ 188	$ 143	$ 725	$ 313