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Discontinued operations - Revenue and Expenses (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]        
Net loss $ 0 $ (85,729) $ 0 $ (170,033)
2seventy bio | Discontinued Operations, Disposed of by Means Other than Sale, Spinoff        
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]        
Total revenues   7,329   19,230
Research and development   59,670   131,305
Selling, general and administrative   23,592   46,898
Share of collaboration loss   10,071   10,071
Change in fair value of contingent consideration   47   416
Total operating expenses   93,466   190,481
Loss from operations   (86,137)   (171,251)
Interest income, net   220   576
Other income, net   188   642
Loss before income taxes   (85,729)   (170,033)
Income tax benefit (expense)   0   0
Net loss   (85,729)   (170,033)
2seventy bio | Discontinued Operations, Disposed of by Means Other than Sale, Spinoff | Service revenue        
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]        
Total revenues   5,314   11,232
2seventy bio | Discontinued Operations, Disposed of by Means Other than Sale, Spinoff | Collaborative arrangement revenue        
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]        
Total revenues   1,670   3,190
2seventy bio | Discontinued Operations, Disposed of by Means Other than Sale, Spinoff | Other revenue        
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]        
Total revenues   345   4,808
Cost of royalty and other revenue   $ 86   $ 1,791