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Discontinued operations (Tables)
6 Months Ended
Jun. 30, 2022
Discontinued Operations and Disposal Groups [Abstract]  
Summary of Revenues , Expenses, Non-cash Items and Capital Expenditures for Discontinued Operations The following table summarizes revenue and expenses of the discontinued operations for the three and six months ended June 30, 2021 (in thousands):
Three months ended June 30, 2021Six months ended June 30, 2021
Revenue:
Service revenue$5,314 $11,232 
Collaborative arrangement revenue1,670 3,190 
Royalty and other revenue345 4,808 
Total revenues7,329 19,230 
Operating expenses:
Research and development59,670 131,305 
Selling, general and administrative23,592 46,898 
Share of collaboration loss10,071 10,071 
Cost of royalty and other revenue86 1,791 
Change in fair value of contingent consideration47 416 
Total operating expenses93,466 190,481 
Loss from operations(86,137)(171,251)
Interest income, net220 576 
Other income, net188 642 
Loss before income taxes(85,729)(170,033)
Income tax benefit (expense)— — 
Net loss$(85,729)$(170,033)
The following table summarizes the significant non-cash items and capital expenditures of the discontinued operations that are included in the condensed consolidated statements of cash flows for the six months ended June 30, 2021 (in thousands):
Six months ended June 30, 2021
Operating activities:
Change in fair value of contingent consideration$416 
Depreciation and amortization8,300 
Stock-based compensation expense19,104 
Loss on fixed asset disposal254 
Investing activities:
Purchase of property, plant and equipment$(7,675)
Purchase of intangible assets(2,000)
Supplemental cash flow disclosures:
Purchases of property, plant and equipment included in accounts payable and accrued expenses$1,345 
Purchases of intangible assets included in accounts payable and accrued expenses, net of reimbursement receivable from collaboration partner6,500