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Accrued expenses and other current liabilities
6 Months Ended
Jun. 30, 2022
Payables and Accruals [Abstract]  
Accrued expenses and other current liabilities Accrued expenses and other current liabilities
Accrued expenses and other current liabilities consist of the following (in thousands):
As of June 30, 2022As of December 31, 2021
Accrued manufacturing costs$18,530 $15,722 
Accrued goods and services14,567 24,273 
Accrued clinical and contract research organization costs18,069 17,769 
Accrued employee compensation19,853 41,095 
Accrued professional fees1,226 1,665 
Deferred revenue, current portion1,635 2,282 
Other1,670 1,152 
Total accrued expenses and other current liabilities$75,550 $103,958 

Accrued employee compensation as of December 31, 2021 includes severance costs associated with the Company's orderly wind down of its European operations. In April 2022, the Company announced a restructuring which included a reduction in force. As of June 30, 2022, the Company had $2.7 million of accrued employee compensation related to the April 2022 restructuring. Please refer to Note 14, Reduction in workforce, for further information.