Condensed Consolidated Statements of Operations and Comprehensive Loss (unaudited) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Revenue:
Total revenues	$ 1,945	$ 894
Operating expenses:
Research and development	77,875	82,843
Selling, general and administrative	36,106	63,569
Cost of product revenue	8,310	576
Total operating expenses	122,291	146,988
Loss from operations	(120,346)	(146,094)
Interest income, net	106	355
Other (expense) income, net	(1,912)	24,301
Loss before income taxes	(122,152)	(121,438)
Income tax (expense) benefit	0	(66)
Net loss from continuing operations	(122,152)	(121,504)
Net loss from discontinued operations	0	(84,304)
Net loss	$ (122,152)	$ (205,808)
Net loss per share from continuing operations - basic (in dollars per share)	$ (1.66)	$ (1.81)
Net loss per share from continuing operations - diluted (in dollars per share)	(1.66)	(1.81)
Net loss per share from discontinued operations - basic (in dollars per share)	0	(1.26)
Net loss per share from discontinued operations - diluted (in dollars per share)	0	(1.26)
Net loss per share - basic (in dollars per share)	(1.66)	(3.07)
Net loss per share - diluted (in dollars per share)	$ (1.66)	$ (3.07)
Weighted-average number of common shares used in computing net loss per share - basic (in shares)	73,688	66,976
Weighted-average number of common shares used in computing net loss per share - diluted (in shares)	73,688	66,976
Other comprehensive (loss) income:
Other comprehensive income (loss)	$ (1,548)	$ 56
Comprehensive loss	(123,700)	(205,752)
Product revenue
Revenue:
Revenue	1,408	724
Other revenue
Revenue:
Revenue	$ 537	$ 170