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Discontinued operations - Revenue and Expenses (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]    
Net loss $ 0 $ (84,304)
2seventy bio | Discontinued Operations, Disposed of by Means Other than Sale, Spinoff    
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]    
Total revenues   11,900
Research and development   71,635
Selling, general and administrative   23,305
Change in fair value of contingent consideration   369
Total operating expenses   97,014
Loss from operations   (85,114)
Interest income, net   355
Other income, net   455
Loss before income taxes   (84,304)
Income tax benefit (expense)   0
Net loss   (84,304)
2seventy bio | Discontinued Operations, Disposed of by Means Other than Sale, Spinoff | Service revenue    
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]    
Total revenues   5,918
2seventy bio | Discontinued Operations, Disposed of by Means Other than Sale, Spinoff | Collaborative arrangement revenue    
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]    
Total revenues   1,519
2seventy bio | Discontinued Operations, Disposed of by Means Other than Sale, Spinoff | Other revenue    
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]    
Total revenues   4,463
Cost of royalty and other revenue   $ 1,705