Intangible assets - Schedule of Finite-Lived Intangible Assets (Details) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Finite-Lived Intangible Assets [Line Items]
Cost	$ 5,224	$ 5,224
Accumulated amortization	(1,219)	(827)
Impairment	(4,005)	0
Net	0	4,397
In-licensed rights
Finite-Lived Intangible Assets [Line Items]
Cost	5,224	5,224
Accumulated amortization	(1,219)	(827)
Impairment	(4,005)	0
Net	$ 0	$ 4,397