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Accrued expenses and other current liabilities
12 Months Ended
Dec. 31, 2021
Payables and Accruals [Abstract]  
Accrued expenses and other current liabilities Accrued expenses and other current liabilities
Accrued expenses and other current liabilities consist of the following (in thousands):
As of December 31,
2021
2020 (1)
Employee compensation$41,095 $41,192 
Accrued goods and services24,273 14,855 
Accrued clinical and contract research organization costs17,769 20,912 
Accrued manufacturing costs15,722 15,763 
Accrued professional fees1,665 1,541 
Deferred revenue, current portion2,282 1,500 
Other1,152 2,427 
Total accrued expenses and other current liabilities$103,958 $98,190 
(1) Prior period amounts have been retrospectively adjusted to reflect the effects of the Separation.
Accrued employee compensation includes severance costs associated with the Company's orderly wind down of its European operations. As of December 31, 2021, the Company had accrued expenses of $4.7 million related to these restructuring costs. Please refer to Note 17, Reduction in workforce, for further discussion.