XML 33 R16.htm IDEA: XBRL DOCUMENT v3.22.0.1
Property, plant and equipment, net
 12 Months Ended
Dec. 31, 2021
Property, Plant and Equipment [Abstract]  
Property, plant and equipment, net Property, plant and equipment, net
Property, plant and equipment, net, consists of the following (in thousands):
As of December 31,
2021
2020 (1)
Laboratory equipment$29,061 $27,146 
Computer equipment and software421 447 
Office equipment117 1,077 
Leasehold improvements12 5,949 
Construction-in-progress501 895 
Total property, plant and equipment30,112 35,514 
Less accumulated depreciation and amortization(20,406)(18,141)
Property, plant and equipment, net$9,706 $17,373 
(1) Prior period amounts have been retrospectively adjusted to reflect the effects of the Separation.
Depreciation and amortization expense related to property, plant and equipment was $4.9 million, $5.1 million, and $4.1 million for the years ended December 31, 2021, 2020, and 2019, respectively.