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Property, plant and equipment, net (Tables)
9 Months Ended
Sep. 30, 2021
Property, Plant and Equipment [Abstract]  
Summary of Property, Plant and Equipment Net Property, plant and equipment, net, consists of the following (in thousands):
As of September 30, 2021As of December 31, 2020
Land
$— $1,210 
Building
— 15,745 
Computer equipment and software
5,699 6,950 
Office equipment
6,686 7,665 
Laboratory equipment
59,673 55,521 
Leasehold improvements
31,579 34,286 
Construction-in-progress
875 92,514 
Total property, plant and equipment
104,512 213,891 
Less accumulated depreciation and amortization
(58,767)(51,060)
Property, plant and equipment, net
$45,745 $162,831