Property, plant and equipment, net

6 Months Ended

Jun. 30, 2021

Property, Plant and Equipment [Abstract]

Property, plant and equipment, net, consists of the following (in thousands):


	As of June 30, 2021		As of December 31, 2020
Land	$	1,210	$	1,210
Building	88,942		15,745
Computer equipment and software	6,919		6,950
Office equipment	7,335		7,665
Laboratory equipment	67,313		55,521
Leasehold improvements	31,259		34,286
Construction-in-progress	14,803		92,514
Total property, plant and equipment	217,781		213,891
Less accumulated depreciation and amortization	(58,961)		(51,060)
Property, plant and equipment, net	$	158,820	$	162,831

North Carolina manufacturing facility

In November 2017, the Company acquired a manufacturing facility in Durham, North Carolina for the future manufacture of lentiviral vector for the Company’s gene therapies. As of June 30, 2021, the majority of the facility has been placed into service. The remainder of the facility is still in process of qualification, which is required for the facility to be ready for its intended use. Construction-in-progress as of June 30, 2021 and December 31, 2020 includes $14.1 million and $91.1 million, respectively, related to the North Carolina manufacturing facility.