Property, plant and equipment, net - Summary of Property, Plant and Equipment Net (Detail) - USD ($) $ in Thousands	Mar. 31, 2021	Dec. 31, 2020
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	$ 219,996	$ 213,891
Less accumulated depreciation and amortization	(54,798)	(51,060)
Property, plant and equipment, net	165,198	162,831
Land
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	1,210	1,210
Building
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	88,591	15,745
Computer equipment and software
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	6,919	6,950
Office equipment
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	7,633	7,665
Laboratory equipment
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	66,600	55,521
Leasehold improvements
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	34,104	34,286
Construction-in-progress
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	$ 14,939	$ 92,514