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Accrued expenses and other current liabilities (Tables)
12 Months Ended
Dec. 31, 2020
Payables and Accruals [Abstract]  
Summary of accrued expenses and other current liabilities Accrued expenses and other current liabilities consist of the following (in thousands):
As of December 31,
20202019
Employee compensation$55,802 $44,679 
Manufacturing costs22,571 23,126 
Clinical and contract research organization costs23,766 16,799 
Collaboration research costs20,004 27,142 
Property, plant, and equipment789 2,354 
License and milestone fees278 300 
Professional fees1,541 1,827 
Other20,655 25,329 
Total accrued expenses and other current liabilities$145,406 $141,556