XML 29 R13.htm IDEA: XBRL DOCUMENT v3.20.4
Property, plant and equipment, net
 12 Months Ended
Dec. 31, 2020
Property, Plant and Equipment [Abstract]  
Property, plant and equipment, net Property, plant and equipment, net
Property, plant and equipment, net, consists of the following (in thousands):
As of December 31,
20202019
Land$1,210 $1,210 
Building15,745 15,664 
Computer equipment and software6,950 6,947 
Office equipment7,665 7,599 
Laboratory equipment55,521 44,560 
Leasehold improvements34,286 33,788 
Construction-in-progress92,514 77,981 
Total property, plant and equipment213,891 187,749 
Less accumulated depreciation and amortization(51,060)(36,573)
Property, plant and equipment, net$162,831 $151,176 
Depreciation and amortization expense related to property, plant and equipment was $15.1 million, $13.4 million, and $13.4 million for the years ended December 31, 2020, 2019, and 2018, respectively.
North Carolina manufacturing facility
In November 2017, the Company acquired a manufacturing facility in Durham, North Carolina for the future manufacture of lentiviral vector for the Company’s gene therapies. As of December 31, 2020, a portion of the facility has been placed into service and the remainder of the facility is still in process of construction and qualification, which is required for the facility to be ready for its intended use.  Construction-in-progress as of December 31, 2020, and 2019, includes $91.1 million and $74.2 million, respectively, related to the North Carolina manufacturing facility.