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Property, plant and equipment, net (Tables)
 3 Months Ended
Mar. 31, 2020
Property, Plant and Equipment [Abstract]  
Summary of Property, Plant and Equipment Net
Property, plant and equipment, net, consists of the following (in thousands):
As of March 31, 2020As of December 31, 2019
Land
$1,210  $1,210  
Building
15,745  15,664  
Computer equipment and software
6,837  6,947  
Office equipment
7,607  7,599  
Laboratory equipment
46,832  44,560  
Leasehold improvements
33,953  33,788  
Construction-in-progress
82,048  77,981  
Total property, plant and equipment
194,232  187,749  
Less accumulated depreciation and amortization
(40,312) (36,573) 
Property, plant and equipment, net
$153,920  $151,176