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Intangible assets - Additional Information (Detail) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Finite-Lived Intangible Assets [Line Items]      
Amortization expense $ 4.1 $ 3.8 $ 3.8
Developed technology      
Finite-Lived Intangible Assets [Line Items]      
Gene editing platform expected useful life 8 years    
In-licensed rights      
Finite-Lived Intangible Assets [Line Items]      
Gene editing platform expected useful life 10 years