Property, plant and equipment, net - Summary of Property, Plant and Equipment Net (Detail) - USD ($) $ in Thousands	Dec. 31, 2019	Dec. 31, 2018
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	$ 187,749	$ 275,798
Less accumulated depreciation and amortization	(36,573)	(29,176)
Property, plant and equipment, net	151,176	246,622
Land
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	1,210	1,210
Building
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	15,664	180,094
Computer equipment and software
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	6,947	6,365
Office equipment
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	7,599	5,584
Laboratory equipment
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	44,560	35,693
Leasehold improvements
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	33,788	183
Construction-in-progress
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	$ 77,981	$ 46,669