Stockholders equity (Details) - $ / shares		3 Months Ended
		Mar. 31, 2025	Dec. 31, 2024
Class of Warrant or Right [Line Items]
Shares of common stock subject to warrants		1,092,569	1,092,572
February 2015 [Member] | Warrants Exercise Price One [Member]
Class of Warrant or Right [Line Items]
Exercise price (in dollars per share)		$ 660,000.00
Expiration		February 2025
Shares of common stock subject to warrants			3
November 2020 [Member] | Warrants Exercise Price One [Member]
Class of Warrant or Right [Line Items]
Exercise price (in dollars per share)		$ 504.40
Expiration		May 2026
Shares of common stock subject to warrants		1,211	1,211
February 2021 [Member] | Warrants Exercise Price One [Member]
Class of Warrant or Right [Line Items]
Exercise price (in dollars per share)		$ 780.00
Expiration		August 2026
Shares of common stock subject to warrants		2,084	2,084
May 2023 [Member] | Warrants Exercise Price One [Member]
Class of Warrant or Right [Line Items]
Exercise price (in dollars per share)		$ 7.785
Expiration	[1]
Shares of common stock subject to warrants		889,274	889,274
October 2023 [Member] | Warrants Exercise Price One [Member]
Class of Warrant or Right [Line Items]
Exercise price (in dollars per share)		$ 3.36
Expiration		April 2029
Shares of common stock subject to warrants		200,000	200,000

[1] Warrants will be exercisable beginning on the date of stockholder approval of the exercisability of the warrants under Nasdaq rules. Once exercisable, the warrants will expire on the five-year anniversary of the date of such stockholder approval.