Stockholders equity (Details 3) - $ / shares		12 Months Ended
		Dec. 31, 2024	Dec. 31, 2023	May 31, 2023
Class of Warrant or Right [Line Items]
Exercise price (in dollars per share)				$ 7.785
Shares of common stock subject to warrants		1,092,572	1,095,517
February 2015 [Member] | Warrants Exercise Price One [Member]
Class of Warrant or Right [Line Items]
Exercise price (in dollars per share)		$ 660,000.00
Expiration		February 2025
Shares of common stock subject to warrants		3	3
October 2019 [Member] | Warrant Exercise Price Two [Member]
Class of Warrant or Right [Line Items]
Exercise price (in dollars per share)		$ 400.00
Shares of common stock subject to warrants			1,770
October 2019 [Member] | Warrant Exercise Price Four [Member]
Class of Warrant or Right [Line Items]
Expiration		October 2024
October 2019 [Member] | Warrants Exercise Price Three [Member]
Class of Warrant or Right [Line Items]
Exercise price (in dollars per share)		$ 520.00
Shares of common stock subject to warrants			1,175
October 2019 [Member] | Warrants Exercise Price Five [Member]
Class of Warrant or Right [Line Items]
Expiration		October 2024
November 2020 [Member] | Warrants Exercise Price Four [Member]
Class of Warrant or Right [Line Items]
Exercise price (in dollars per share)		$ 504.40
Shares of common stock subject to warrants		1,211	1,211
November Twenty Thousand Twenty [Member] | Warrants Exercise Price Ten [Member]
Class of Warrant or Right [Line Items]
Expiration		May 2026
February 2021 [Member] | Warrants Exercise Price Five [Member]
Class of Warrant or Right [Line Items]
Exercise price (in dollars per share)		$ 780.00
Shares of common stock subject to warrants		2,084	2,084
February Twenty Thousand Twenty One [Member] | Warrants Exercise Price Seven [Member]
Class of Warrant or Right [Line Items]
Expiration		August 2026
May 2023 [Member] | Warrant Exercise Price Six [Member]
Class of Warrant or Right [Line Items]
Exercise price (in dollars per share)		$ 7.79
Shares of common stock subject to warrants	[1]	889,274	889,274
October 2023 [Member] | Warrant Exercise Price Seven [Member]
Class of Warrant or Right [Line Items]
Exercise price (in dollars per share)		$ 3.36
Shares of common stock subject to warrants		200,000	200,000
October Twenty Thousand Twenty Three [Member] | Warrant Exercise Price Ten [Member]
Class of Warrant or Right [Line Items]
Expiration		April 2029

[1] Warrants will be exercisable beginning on the date of stockholder approval of the exercisability of the warrants under Nasdaq rules. Once exercisable, the warrants will expire on the five-year anniversary of the date of such stockholder approval.