Stockholders equity (Details 1) - Equity Option [Member] - USD ($)	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Number of options, outstanding at beginning	9,624	10,761
Weighted- average exercise price, outstanding at beginning	$ 1,064.84	$ 934.50
Weighted- average remaining contractual life (in years), outstanding	7 years 6 months	6 years 9 months 18 days	7 years 10 months 24 days
Aggregate intrinsic value, outstanding at beginning
Number of options, granted
Weighted- average exercise price, granted
Number of options, exercised
Weighted- average exercise price, exercised
Number of options, forfeited	(892)	(420)
Weighted- average exercise price, forfeited	$ 314.61	$ 299.80
Number of options, expired	(8,594)	(717)
Weighted- average exercise price, expired	$ 1,158.04	$ 1,012.10
Number of options, outstanding at ending	138	9,624	10,761
Weighted- average exercise price, outstanding at ending	$ 110.26	$ 1,064.84	$ 934.50
Aggregate intrinsic value, outstanding at ending
Number of options, vested and expected to vest	138
Weighted- average exercise price, vested and expected to vest	$ 110.26
Weighted- average remaining contractual life (in years), vested and expected to vest	7 years 6 months
Aggregate intrinsic value, vested and expected to vest
Number of options, exercisable	138
Weighted- average exercise price, exercisable	$ 110.26
Weighted- average remaining contractual life (in years), exercisable	7 years 6 months
Aggregate intrinsic value, exercisable