Stockholders' Equity (Deficit) - Warrants to Purchase Shares of Common Stock (Details) - $ / shares	9 Months Ended
	Sep. 30, 2019	Dec. 31, 2018
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Shares of Common Stock Subject to Warrants	175,982	175,990
November 2009 [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Exercise Price	$ 3,955.00
Expiration	2019-11
Shares of Common Stock Subject to Warrants	17	17
January 2010 [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Exercise Price	$ 3,955.00
Expiration	2020-01
Shares of Common Stock Subject to Warrants	17	17
March 2010 [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Exercise Price	$ 3,955.00
Expiration	2020-03
Shares of Common Stock Subject to Warrants	7	7
November 2011 [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Exercise Price	$ 3,955.00
Expiration	2021-11
Shares of Common Stock Subject to Warrants	15	15
December 2011 [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Exercise Price	$ 3,955.00
Expiration	2021-12
Shares of Common Stock Subject to Warrants	2	2
March 2012 [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Exercise Price	$ 54,950.00
Expiration	2019-03
Shares of Common Stock Subject to Warrants		8
February 2015 [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Exercise Price	$ 3,300.00
Expiration	2025-02
Shares of Common Stock Subject to Warrants	451	451
May 2015 [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Exercise Price	$ 3,300.00
Expiration	2020-05
Shares of Common Stock Subject to Warrants	6,555	6,555
May 2016 [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Exercise Price	$ 656.00
Expiration	2021-05
Shares of Common Stock Subject to Warrants	9,483	9,483
June 2016 [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Exercise Price	$ 656.00
Expiration	2021-05
Shares of Common Stock Subject to Warrants	4,102	4,102
June 2017 [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Exercise Price	$ 390.00
Expiration	2022-06
Shares of Common Stock Subject to Warrants	938	938
July 2017 [Member] | Exercise Price 17.25 [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Exercise Price	$ 345.00
Expiration	2022-07
Shares of Common Stock Subject to Warrants	318	318
July 2017 [Member] | Exercise Price 12.50 [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Exercise Price	$ 250.00
Expiration	2022-07
Shares of Common Stock Subject to Warrants	2,501	2,501
July 2017 [Member] | Exercise Price 10.63 [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Exercise Price	$ 212.60
Expiration	2022-07
Shares of Common Stock Subject to Warrants	50,006	50,006
February 2018 [Member] | Exercise Price 4.06 [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Exercise Price	$ 81.20
Expiration	2023-02
Shares of Common Stock Subject to Warrants	9,232	9,232
February 2018 [Member] | Exercise Price 3.25 [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Exercise Price	$ 65.00
Expiration	2023-02
Shares of Common Stock Subject to Warrants	92,338	92,338