Liquidity and Management's Plans - Additional Information (Details) - USD ($)								1 Months Ended	3 Months Ended		12 Months Ended
	Mar. 29, 2019	Oct. 22, 2018	Jul. 30, 2018	Jul. 14, 2018	Jun. 11, 2018	Feb. 06, 2018	Sep. 13, 2016	Jul. 31, 2015	Mar. 31, 2019	Mar. 31, 2018	Dec. 31, 2018
Conversion Of Stock [Line Items]
Proceeds from issuance of common stock, net of issuance costs									$ 4,782,509	$ 0
Net proceeds from sale of common stock and warrants									$ 0	$ 10,721,401
MGHIF Financing Agreement [Member]
Conversion Of Stock [Line Items]
Stock issued during period, shares, new issues								45,454
Shares issued, price per share								$ 110.00
Proceeds from issuance of common stock, net of issuance costs								$ 5,000,000
Aggregate principal amount								$ 1,000,000
MGHIF Financing Agreement [Member] | The Allonge [Member]
Conversion Of Stock [Line Items]
Aggregate principal amount					$ 1,000,000
Accrued and unpaid interest				$ 285,512
Revised and extended maturity date for payment, terms					Six semi-annual payments
Principal payments includes accrued and unpaid interest					$ 166,667
Beginning date of debt maturity					Jan. 02, 2019
Ending date of debt maturity					Jul. 01, 2021
February 2018 Public Offering [Member]
Conversion Of Stock [Line Items]
Stock issued during period, shares, new issues						2,841,152
Shares issued, price per share						$ 3.25
Gross proceeds from sale of common stock and warrants						$ 12,000,000
Net proceeds from sale of common stock and warrants						$ 10,700,000
Sale of stock, description of transaction									Each unit included one share of common stock and one common warrant to purchase 0.5 share of common stock at an exercise price of $3.25 per share. Each pre-funded unit included one pre-funded warrant to purchase one share of common stock for an exercise price of $0.01 per share, and one common warrant to purchase 0.5 share of common stock at an exercise price of $3.25 per share.
Class of warrant or right, number of securities called by each warrant or right						0.5
Class of warrant or right, exercise price of warrants or rights						$ 3.25
Warrants exercisable period						5 years
At the Market Offering [Member] | Cowen and Company, LLC [Member] | Sales Agreement [Member]
Conversion Of Stock [Line Items]
Gross proceeds from sale of common stock											$ 600,000
Proceeds from issuance of common stock, net of issuance costs											$ 600,000
Stock issued during period, value, new issues							$ 11,500,000
At the Market Offering [Member] | Cowen and Company, LLC [Member] | Sales Agreement [Member] | Maximum [Member]
Conversion Of Stock [Line Items]
Aggregate gross proceeds from issuance of common stock							$ 25,000,000
Common Stock [Member] | October 2018 Public Offering [Member]
Conversion Of Stock [Line Items]
Stock issued during period, shares, new issues		2,220,000
Shares issued, price per share		$ 1.45
Gross proceeds from sale of common stock		$ 3,200,000
Proceeds from issuance of common stock, net of issuance costs		$ 2,800,000
Common Stock [Member] | March 2019 Public Offering [Member]
Conversion Of Stock [Line Items]
Stock issued during period, shares, new issues	9,000,000
Shares issued, price per share	$ 0.60
Gross proceeds from sale of common stock	$ 5,400,000
Proceeds from issuance of common stock, net of issuance costs	$ 4,800,000
Common Stock [Member] | Private Placement [Member] | MGHIF Financing Agreement [Member] | The Allonge [Member]
Conversion Of Stock [Line Items]
Stock issued during period, shares, new issues			144,238
Accrued and unpaid interest			$ 285,512
Accrued and unpaid interest due date			Jul. 14, 2018
Common Stock [Member] | At the Market Offering [Member] | Cowen and Company, LLC [Member] | Sales Agreement [Member]
Conversion Of Stock [Line Items]
Stock issued during period, shares, new issues											318,236
Pre-funded Units [Member] | February 2018 Public Offering [Member]
Conversion Of Stock [Line Items]
Stock issued during period, shares, new issues						851,155
Shares issued, price per share						$ 3.24
Pre-funded Warrants [Member] | February 2018 Public Offering [Member]
Conversion Of Stock [Line Items]
Class of warrant or right, exercise price of warrants or rights						$ 0.01
Warrants exercised											851,155