XML 34 R24.htm IDEA: XBRL DOCUMENT v3.8.0.1
Liquidity and Management's Plans - Additional Information (Details) - USD ($)
1 Months Ended 3 Months Ended 19 Months Ended
Feb. 06, 2018
Jul. 18, 2017
Jun. 28, 2017
May 31, 2017
Sep. 13, 2016
Jul. 31, 2017
Mar. 31, 2018
Mar. 31, 2017
Mar. 31, 2018
Jun. 30, 2017
Conversion Of Stock [Line Items]                    
Net proceeds from sale of common stock and warrants             $ 10,721,401 $ 0    
Net proceeds from sale of common stock             $ 0 $ 2,122,861    
Merck GHI Financing Agreement [Member]                    
Conversion Of Stock [Line Items]                    
Interest rate     10.00%              
Maturity date             Jul. 14, 2017      
Debt instrument, extended maturity date             Jul. 14, 2018      
Percentage of warrants to purchase common stock shares on outstanding principal and accrued interest on issuance date     20.00%              
Bridge Financing Notes [Member] | Note Purchase Agreement [Member]                    
Conversion Of Stock [Line Items]                    
Interest rate       10.00%            
Maturity date       Sep. 30, 2017            
Bridge Financing Notes [Member] | Note Purchase Agreement [Member] | Maximum [Member]                    
Conversion Of Stock [Line Items]                    
Aggregate principal amount       $ 1,500,000            
Bridge Financing Note One [Member] | Note Purchase Agreement [Member]                    
Conversion Of Stock [Line Items]                    
Aggregate principal amount       500,000            
Bridge Financing Note Two [Member] | Note Purchase Agreement [Member]                    
Conversion Of Stock [Line Items]                    
Aggregate principal amount       500,000            
Bridge Financing Note Three [Member] | Note Purchase Agreement [Member]                    
Conversion Of Stock [Line Items]                    
Aggregate principal amount       $ 500,000            
Qualified Financing [Member] | Note Purchase Agreement [Member] | Minimum [Member]                    
Conversion Of Stock [Line Items]                    
Net proceeds from equity or debt financing             $ 5,000,000      
Stock Purchase Warrants [Member] | Bridge Financing Notes [Member] | Note Purchase Agreement [Member]                    
Conversion Of Stock [Line Items]                    
Class of warrant or right, exercise price of warrants or rights                   $ 19.50
Class of warrant or right, number of securities called by warrants or rights                   5,634
Warrants [Member] | Bridge Financing Notes [Member] | Note Purchase Agreement [Member]                    
Conversion Of Stock [Line Items]                    
Class of warrant or right, exercise price of warrants or rights           $ 17.25        
Class of warrant or right, number of securities called by warrants or rights           6,350        
February 2018 Public Offering [Member]                    
Conversion Of Stock [Line Items]                    
Stock issued during period, shares, new issues 2,841,152                  
Shares issued, price per share $ 3.25                  
Gross proceeds from sale of common stock and warrants $ 12,000,000                  
Net proceeds from sale of common stock and warrants $ 10,700,000                  
Sale of stock, description of transaction             Each unit included one share of common stock and one common warrant to purchase 0.5 share of common stock at an exercise price of $3.25 per share. Each pre-funded unit included one pre-funded warrant to purchase one share of common stock for an exercise price of $0.01 per share, and one common warrant to purchase 0.5 share of common stock at an exercise price of $3.25 per share.      
Class of warrant or right, number of securities called by each warrant or right 0.5                  
Class of warrant or right, exercise price of warrants or rights $ 3.25                  
Warrants exercisable period 5 years                  
February 2018 Public Offering [Member] | Pre-funded Units [Member]                    
Conversion Of Stock [Line Items]                    
Stock issued during period, shares, new issues 851,155                  
Shares issued, price per share $ 3.24                  
February 2018 Public Offering [Member] | Pre-funded Warrants [Member]                    
Conversion Of Stock [Line Items]                    
Class of warrant or right, exercise price of warrants or rights $ 0.01                  
July 2017 Public Offering [Member]                    
Conversion Of Stock [Line Items]                    
Stock issued during period, shares, new issues   18,164,195                
Shares issued, price per share   $ 0.40                
Gross proceeds from sale of common stock and warrants   $ 10,000,000                
Net proceeds from sale of common stock and warrants   $ 8,800,000                
Sale of stock, description of transaction             Each unit included one twenty-fifth of a share of common stock and one common warrant to purchase one twenty-fifth of a share of common stock at an exercise price of $10.625 per share. Each pre-funded unit included one pre-funded warrant to purchase one twenty-fifth of a share of common stock for an exercise price of $0.25 per share, and one common warrant to purchase one twenty-fifth of a share of common stock at an exercise price of $10.625 per share.      
Class of warrant or right, number of securities called by each warrant or right   0.04                
Class of warrant or right, exercise price of warrants or rights   $ 10.625                
Warrants exercisable period   5 years                
July 2017 Public Offering [Member] | Bridge Financing Notes [Member]                    
Conversion Of Stock [Line Items]                    
Repayment of outstanding debt   $ 1,000,000       $ 1,000,000        
July 2017 Public Offering [Member] | Pre-funded Units [Member]                    
Conversion Of Stock [Line Items]                    
Stock issued during period, shares, new issues   6,835,805                
Shares issued, price per share   $ 0.39                
July 2017 Public Offering [Member] | Pre-funded Warrants [Member]                    
Conversion Of Stock [Line Items]                    
Class of warrant or right, number of securities called by each warrant or right   0.04                
Class of warrant or right, exercise price of warrants or rights   $ 0.25                
At the Market Offering [Member] | Sales Agreement [Member] | Cowen and Company, LLC [Member]                    
Conversion Of Stock [Line Items]                    
Stock issued during period, value, new issues         $ 11,500,000          
Net proceeds from sale of common stock             $ 8,200,000      
Gross proceeds from sale of common stock             8,800,000      
Remaining availability under at the market offering             $ 2,700,000      
At the Market Offering [Member] | Sales Agreement [Member] | Maximum [Member] | Cowen and Company, LLC [Member]                    
Conversion Of Stock [Line Items]                    
Aggregate gross proceeds from issuance of common stock         $ 25,000,000          
At the Market Offering [Member] | Common Stock [Member] | Sales Agreement [Member] | Cowen and Company, LLC [Member]                    
Conversion Of Stock [Line Items]                    
Stock issued during period, shares, new issues             0   372,011