Debt	3 Months Ended
Mar. 31, 2018
Debt Disclosure [Abstract]
Debt	Note 7 - Debt As of March 31, 2018, the Company’s outstanding short-term debt consisted of the MGHIF Note, net of discounts and financing costs (see Note 5 “MGHIF Financing”), as well as, the financing arrangements for the Company’s insurance with note balances of approximately $7 thousand with a final payment scheduled for May 2018. Total principal payments of $1.0 million are due in July 2018. As of December 31, 2017, the Company's outstanding short-term debt consisted of the $1.0 million MGHIF Note, net of discounts and financing costs as well as, the financing arrangements for the Company's insurance with note balances of approximately $0.1 million. The Company drew down on two of three Bridge Financing Notes (see discussion in Note 2 “Liquidity and management’s plans”) during June and July of 2017. The outstanding Bridge Financing Notes were repaid in full subsequent to the closing of the July 2017 Public Offering. The Company accounted for the embedded conversion option granted to jVen Capital in the Bridge Financing Notes as a mark-to-market derivative financial instrument carried at fair value. Changes in fair value of the embedded conversion option were reflected in earnings during the period of change. The embedded conversion option was expensed along with the remaining unamortized discount at the date of the Bridge Financing Notes repayment. The warrants issued to jVen Capital and MGHIF are classified as mark-to-market liabilities under ASC 480 due to certain put features that allow the holder to put the warrant back to the Company for cash equal to the Black-Scholes value of the warrant upon a change of control or fundamental transaction. Total interest expense (including amortization of debt discounts and financing fees) on all debt instruments was $57,846 and $29,844 for the three months ended March 31, 2018 and 2017, respectively.

Note 7 - Debt

As of March 31, 2018, the Company’s outstanding short-term debt consisted of the MGHIF Note, net of discounts and financing costs (see Note 5 “MGHIF Financing”), as well as, the financing arrangements for the Company’s insurance with note balances of approximately $7 thousand with a final payment scheduled for May 2018. Total principal payments of $1.0 million are due in July 2018. As of December 31, 2017, the Company's outstanding short-term debt consisted of the $1.0 million MGHIF Note, net of discounts and financing costs as well as, the financing arrangements for the Company's insurance with note balances of approximately $0.1 million.

The Company drew down on two of three Bridge Financing Notes (see discussion in Note 2 “Liquidity and management’s plans”) during June and July of 2017. The outstanding Bridge Financing Notes were repaid in full subsequent to the closing of the July 2017 Public Offering.

The Company accounted for the embedded conversion option granted to jVen Capital in the Bridge Financing Notes as a mark-to-market derivative financial instrument carried at fair value. Changes in fair value of the embedded conversion option were reflected in earnings during the period of change. The embedded conversion option was expensed along with the remaining unamortized discount at the date of the Bridge Financing Notes repayment. The warrants issued to jVen Capital and MGHIF are classified as mark-to-market liabilities under ASC 480 due to certain put features that allow the holder to put the warrant back to the Company for cash equal to the Black-Scholes value of the warrant upon a change of control or fundamental transaction.

Total interest expense (including amortization of debt discounts and financing fees) on all debt instruments was $57,846 and $29,844 for the three months ended March 31, 2018 and 2017, respectively.