Aggregate gross proceeds from issuance of common stock.

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Represents expiration date of warrants issued during the period.

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Gross proceeds from issuance of common stock.

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Maximum commission percentage on gross proceeds.

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Percentage of grant represent of the total outstanding shares of common stock.

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Remaining available amount under at the market offering.

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Share based compensation arrangement by share based payment award common stock percentage.

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Contractual term of award.

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Exercise per share amount at which grantees can acquire shares of common stock by exercise of options.

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Represents the warrant expiration period.

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Exercise price per share or per unit of warrants or rights outstanding.

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The maximum number of common shares permitted to be issued by an entity's charter and bylaws.

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Total number of common shares of an entity that have been sold or granted to shareholders (includes common shares that were issued, repurchased and remain in the treasury). These shares represent capital invested by the firm's shareholders and owners, and may be all or only a portion of the number of shares authorized. Shares issued include shares outstanding and shares held in the treasury.

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Number of shares of common stock outstanding. Common stock represent the ownership interest in a corporation.

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The number of shares converted in a noncash (or part noncash) transaction. Noncash is defined as transactions during a period that do not result in cash receipts or cash payments in the period. "Part noncash" refers to that portion of the transaction not resulting in cash receipts or cash payments in the period.

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The total recognized tax benefit related to compensation cost for equity-based payment arrangements recognized in income during the period.

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The maximum number of nonredeemable preferred shares (or preferred stock redeemable solely at the option of the issuer) permitted to be issued by an entity's charter and bylaws.

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Total number of nonredeemable preferred shares (or preferred stock redeemable solely at the option of the issuer) issued to shareholders (includes related preferred shares that were issued, repurchased, and remain in the treasury). May be all or portion of the number of preferred shares authorized. Excludes preferred shares that are classified as debt.

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Aggregate share number for all nonredeemable preferred stock (or preferred stock redeemable solely at the option of the issuer) held by stockholders. Does not include preferred shares that have been repurchased.

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The cash inflow from the additional capital contribution to the entity.

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The cash inflow associated with the amount received from entity's raising of capital via private rather than public placement.

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Description of stock transaction which may include details of the offering (IPO, private placement), a description of the stock sold, percentage of subsidiary's or equity investee's stock sold, a description of the investors and whether the stock was issued in a business combination.

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General descriptive information regarding an arrangement under which employees and directors receive: (a) awards of equity shares, equity share options, or other equity instruments; or (b) the entity incurs liabilities to them: (1) in amounts based, at least in part, on the price of the entity's shares or other equity instruments; or (2) that require or may require settlement by issuance of the entity's shares. Such an arrangement is usually provided to employees and directors to compensate them, provide performance incentives to them, and to attract or retain their services. May also include pertinent information particular to a plan that is not elsewhere specified in the taxonomy.

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The number of equity-based payment instruments, excluding stock (or unit) options, that were forfeited during the reporting period.

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The number of grants made during the period on other than stock (or unit) option plans (for example, phantom stock or unit plan, stock or unit appreciation rights plan, performance target plan).

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The weighted average fair value at grant date for nonvested equity-based awards issued during the period on other than stock (or unit) option plans (for example, phantom stock or unit plan, stock or unit appreciation rights plan, performance target plan).

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The number of non-vested equity-based payment instruments, excluding stock (or unit) options, that validly exist and are outstanding as of the balance sheet date.

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Number of additional shares authorized for issuance under an established share-based compensation plan.

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The maximum number of shares (or other type of equity) originally approved (usually by shareholders and board of directors), net of any subsequent amendments and adjustments, for awards under the equity-based compensation plan. As stock or unit options and equity instruments other than options are awarded to participants, the shares or units remain authorized and become reserved for issuance under outstanding awards (not necessarily vested).

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The difference between the maximum number of shares (or other type of equity) authorized for issuance under the plan (including the effects of amendments and adjustments), and the sum of: 1) the number of shares (or other type of equity) already issued upon exercise of options or other equity-based awards under the plan; and 2) shares (or other type of equity) reserved for issuance on granting of outstanding awards, net of cancellations and forfeitures, if applicable.

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The number of shares under options that were cancelled during the reporting period as a result of occurrence of a terminating event specified in contractual agreements pertaining to the stock option plan.

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Gross number of share options (or share units) granted during the period.

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The weighted average grant-date fair value of options granted during the reporting period as calculated by applying the disclosed option pricing methodology.

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Number of options outstanding, including both vested and non-vested options.

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Weighted average price at which grantees could have acquired the underlying shares with respect to stock options that were terminated.

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Weighted average per share amount at which grantees can acquire shares of common stock by exercise of options.

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Percentage of vesting of share-based compensation awards.

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Number of new stock issued during the period.

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Equity impact of the value of new stock issued during the period. Includes shares issued in an initial public offering or a secondary public offering.

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Stockholders' equity (Details Textual) - USD ($)				1 Months Ended			2 Months Ended	3 Months Ended
Stockholders' equity (Details Textual) - USD ($)	Mar. 31, 2017	Apr. 28, 2016	Jan. 01, 2016	Sep. 30, 2016	Jun. 30, 2016	May 31, 2016	Jun. 30, 2016	Mar. 31, 2017	Mar. 31, 2016	Dec. 31, 2015	Dec. 31, 2016
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Common stock, shares authorized	200,000,000							200,000,000			200,000,000
Common stock, shares issued	27,377,490							27,377,490			25,304,270
Common stock, shares outstanding	27,377,490							27,377,490			25,304,270
Preferred stock, shares authorized	10,000,000							10,000,000			10,000,000
Preferred stock, shares issued	0							0			0
Preferred stock, shares outstanding	0							0			0
Proceeds from issuance of common stock, net of issuance costs								$ 2,122,861	$ 0
Proceeds from issuance of private placement net							$ 9,500,000
Convertible preferred stock, beneficial conversion feature recognized as deemed dividend								$ 332,550
Share-based compensation arrangement by share-based payment award, options, grants in period, gross								723,600
Share-based compensation, tax benefit from compensation expense								$ 0
Share-based compensation arrangements by share-based payment award, options, grants in Period, weighted average exercise price								$ 1.03
Share-based compensation arrangement by share-based payment award, options, forfeitures in period								4,863
Share-based compensation arrangements by share-based payment award, options, forfeitures in period, weighted average exercise price								$ 1.82
Stock options
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-based compensation arrangement by share-based payment award, options, grants in period, weighted average grant date fair value								$ 0.54
Share-based compensation arrangement by share-based payment award, options, outstanding, number	3,514,071							3,514,071
Restricted Stock Units [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-based compensation arrangement by share-based payment award, equity instruments other than options, grants in period										75,000
Share-based compensation arrangement by share-based payment award, equity instruments other than options, grants in period, weighted average grant date fair value										$ 1.70
Share-based compensation arrangement by share-based payment award, equity instruments other than options, non-vested, outstanding	18,750							18,750
Share-based compensation arrangement by share-based payment award, equity instruments other than options, vested in period								0
Share-based compensation arrangement by share-based payment award, equity instruments other than options, forfeited in period								0
Chief Executive Officer [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-based compensation arrangement by share-based payment award, options, grants in period, gross		766,500
Percentage of total outstanding shares of common stock		6.00%
Share based compensation arrangements by share based payment award options grants in period exercise price		$ 1.35
Share based compensation arrangements by share based payment award contractual term		10 years
Chief Executive Officer [Member] \| Share-based Compensation Award, Tranche One [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-based compensation arrangement by share-based payment award, award vesting rights, percentage		25.00%
Chief Executive Officer [Member] \| Share-based Compensation Award, Tranche Two [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-based compensation arrangement by share-based payment award, award vesting rights, percentage		6.25%
2015 Plan [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-based compensation arrangement by share-based payment award, number of shares authorized	1,355,000							1,355,000
Share-based compensation arrangement by share-based payment award, description								the number of shares that have been authorized for issuance under the 2015 Plan will be automatically increased on the first day of each fiscal year beginning on January 1, 2016 and ending on (and including) January 1, 2025, in an amount equal to the lesser of (1) 4% of the outstanding shares of common stock on the last day of the immediately preceding fiscal year, or (2) another lesser amount determined by the Company’s Board of Directors.
Share-based compensation arrangement by share-based payment award, number of shares available for grant	1,145,402							1,145,402
Share-based compensation arrangement by share-based payment award, common stock percentage								4.00%
Share-based compensation arrangement by share-based payment award, number of additional shares authorized			1,012,171
May 2016 Warrant [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Class of warrant or right, exercise price of warrants or rights						$ 1.3125
Warrant expiration period						5 years
Expiration date of warrants issued								May 18, 2021
June 2016 Warrant [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Class of warrant or right, exercise price of warrants or rights					$ 1.3125		$ 1.3125
Warrant expiration period					5 years
Expiration date of warrants issued								May 18, 2021
Common Stock [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Conversion of stock, shares issued								2,309,428
Non-voting Convertible Preferred Stock [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Conversion of stock, shares converted								2,309,428
Private Placement [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Class of warrant or right, number of securities called by each warrant or right					0.75		0.75
Class of warrant or right, number of securities called by warrants or rights					6,790,169		6,790,169
Class of warrant or right, exercise price of warrants or rights					$ 1.14		$ 1.14
Sale of stock, description of transaction								(i) one share of common stock and a detachable stock purchase warrant to purchase an additional 0.75 shares of common stock, or (ii) one share of non-voting convertible preferred stock and a detachable stock purchase warrant to purchase an additional 0.75 shares of common stock, at a price of $1.14 per unit.
Proceeds from issuance of private placement net							$ 9,500,000
Private Placement [Member] \| Common Stock [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Stock issued during period, shares, new issues							6,744,127
Private Placement [Member] \| Non-voting Convertible Preferred Stock [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Stock issued during period, shares, new issues							2,309,428
Cowen and Company, LLC [Member] \| At the Market Offering [Member] \| Sales Agreement [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Stock issued during period, value, new issues				$ 11,500,000
Maximum commission percentage on gross proceeds				3.00%
Remaining availability under at the market offering	$ 4,600,000			$ 4,600,000
Proceeds from issuance of common stock, net of issuance costs	6,500,000							$ 2,100,000
Gross proceeds from sale of common stock	$ 6,900,000							$ 2,200,000
Cowen and Company, LLC [Member] \| At the Market Offering [Member] \| Sales Agreement [Member] \| Common Stock [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Stock issued during period, shares, new issues	5,700,000							2,100,000
Maximum [Member] \| Cowen and Company, LLC [Member] \| At the Market Offering [Member] \| Sales Agreement [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Aggregate gross proceeds from issuance of common stock				$ 25,000,000