Going Concern and Management’s Plans (Details) $ / shares in Units, € in Thousands			1 Months Ended		6 Months Ended		12 Months Ended
	Mar. 09, 2021 USD ($) $ / shares shares	Feb. 11, 2021 USD ($) $ / shares shares	May 23, 2022 EUR (€)	Oct. 18, 2021 USD ($) $ / shares shares	Jun. 30, 2022 USD ($) $ / shares	Jun. 30, 2021 USD ($)	Dec. 31, 2021 USD ($) $ / shares shares	Apr. 30, 2022 EUR (€)	Feb. 28, 2022 USD ($) $ / shares	Feb. 11, 2020 USD ($)
Going Concern and Management’s Plans (Details) [Line Items]
Repaid amount (in Euro) | $					$ 6,819,405	$ 441,076
Preferred stock stated value per share (in Dollars per share) | $ / shares					$ 0.01		$ 0.01
Common Stock, value | $					$ 466,237		$ 464,503
Holder pursuant to company issued to Holder securities [Member] | Warrants [Member]
Going Concern and Management’s Plans (Details) [Line Items]
Aggregate gross proceeds | $	$ 9,650,000
European Investment Bank [Member] | Third Tranches [Member]
Going Concern and Management’s Plans (Details) [Line Items]
Aggregate of borrowing amount (in Euro) | €			€ 18,000
European Investment Bank [Member] | Tranche One [Member]
Going Concern and Management’s Plans (Details) [Line Items]
Accumulated and deferred interest (in Euro) | €			13,350
Repaid amount (in Euro) | €			5,000
Tranche 1 payment (in Euro) | €								€ 5,000
European Investment Bank [Member] | Second Tranches [Member]
Going Concern and Management’s Plans (Details) [Line Items]
Tranche 1 payment (in Euro) | €			€ 3,000
2022 ATM Offering [Member] | H.C. Wainwright & Co., LLC [Member]
Going Concern and Management’s Plans (Details) [Line Items]
Maximum value of common stock shares issuable through sales agent | $					$ 10,650,000
PPI [Member] | European Investment Bank [Member]
Going Concern and Management’s Plans (Details) [Line Items]
Old PPI debt, percentage			0.30%
Increased PPI debt, percentage			0.75%
October 2021 Offering [Member] | Healthcare-focused Institutional Investor [Member]
Going Concern and Management’s Plans (Details) [Line Items]
Shares issued (in Shares) | shares				150,000
Preferred stock stated value per share (in Dollars per share) | $ / shares				$ 100
Converted common shares (in Shares) | shares				7,500,000			7,500,000
Common stock conversion price (in Dollars per share) | $ / shares				$ 2
Exercise price per share (in Dollars per share) | $ / shares				$ 2.05
Warrants expiry period				5 years
Net proceeds | $				$ 13,900,000
Gross proceeds | $				$ 15,000,000
October 2021 Offering [Member] | Healthcare-focused Institutional Investor [Member] | Warrants [Member]
Going Concern and Management’s Plans (Details) [Line Items]
Shares issued (in Shares) | shares				7,500,000
October 2021 Offering [Member] | Healthcare-focused Institutional Investor [Member] | Pre Funded Warrant [Member]
Going Concern and Management’s Plans (Details) [Line Items]
Shares issued (in Shares) | shares				7,500,000
October 2021 Offering [Member] | Investor [Member]
Going Concern and Management’s Plans (Details) [Line Items]
Exercise price per share (in Dollars per share) | $ / shares				$ 2.05
February 2021 Offering [Member]
Going Concern and Management’s Plans (Details) [Line Items]
Exercise price per share (in Dollars per share) | $ / shares		$ 3.55
February 2021 Offering [Member] | Healthcare-focused Institutional Investor [Member]
Going Concern and Management’s Plans (Details) [Line Items]
Shares issued (in Shares) | shares		2,784,184
Preferred stock stated value per share (in Dollars per share) | $ / shares		$ 3
Converted common shares (in Shares) | shares		2.99
Exercise price per share (in Dollars per share) | $ / shares		$ 0.01
Gross proceeds | $		$ 25,000,000
Proceeds from issuances | $		$ 23,500,000
February 2021 Offering [Member] | Healthcare-focused Institutional Investor [Member] | Warrants [Member]
Going Concern and Management’s Plans (Details) [Line Items]
Shares issued (in Shares) | shares		5,549,149
February 2021 Offering [Member] | Healthcare-focused Institutional Investor [Member] | Pre Funded Warrant [Member]
Going Concern and Management’s Plans (Details) [Line Items]
Shares issued (in Shares) | shares		5,549,149					5,549,149
February 2021 Offering [Member] | Investor [Member]
Going Concern and Management’s Plans (Details) [Line Items]
Exercise price per share (in Dollars per share) | $ / shares		$ 3.55
Warrants expiry period		5 years 6 months
Stock and warrants net of issuance costs in shares (in Shares) | shares		4,166,666
Shares issued (in Dollars per share) | $ / shares		$ 3
February 2021 Offering [Member] | Investor [Member] | Pre Funded Warrant [Member]
Going Concern and Management’s Plans (Details) [Line Items]
Exercise price per share (in Dollars per share) | $ / shares		0.01
Shares issued (in Dollars per share) | $ / shares		$ 2.99
Warrant [Member] | Exercise Agreement [Member] | Holder [Member]
Going Concern and Management’s Plans (Details) [Line Items]
Exercise price per share (in Dollars per share) | $ / shares	$ 3.56
Price per common shares (in Shares) | shares	0.65
Common stock shares (in Shares) | shares	3,147,700
Warrants expiry period	5 years
Aggregate gross proceeds | $	$ 255,751
Warrant [Member] | Purchase Agreement [Member] | Alliance Global Partners [Member]
Going Concern and Management’s Plans (Details) [Line Items]
Cash fee compensation | $	$ 200,000
Nasdaq Stock Market LLC [Member]
Going Concern and Management’s Plans (Details) [Line Items]
Per share price (in Dollars per share) | $ / shares									$ 1
Common Stock, value | $									$ 1
2020 ATM Offering [Member] | Common Stock [Member] | H.C. Wainwright & Co., LLC [Member]
Going Concern and Management’s Plans (Details) [Line Items]
Shares issued (in Shares) | shares							680,000
Gross proceeds | $							$ 1,550,000
Proceeds from issuances | $							$ 1,480,000
Aggregate of common stock | $										$ 22,100,000