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Stockholders' Equity - Summary of Status of Options Granted (Details) - USD ($)
3 Months Ended 6 Months Ended 12 Months Ended
Jun. 30, 2019
Jun. 30, 2019
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Stockholders' Equity Note [Abstract]          
Number of Options, Outstanding Balance   211,559 139,395 119,106  
Number of Options, Granted 0 0 95,800 58,324  
Number of Options, Exercised     0 (1,167)  
Number of Options, Forfeited (720) (720) (18,812) (24,538)  
Number of Options, Expired 0 (5) (4,824) (12,330)  
Number of Options, Outstanding Balance 210,834 210,834 211,559 139,395 119,106
Number of Options, Vested and expected to vest     211,559    
Number of Options, Exercisable     10,445    
Weighted Average Exercise Price, Outstanding Balance   $ 20.58 $ 31.16 $ 44.00  
Weighted Average Exercise Price, Granted     3.84 17.58  
Weighted Average Exercise Price, Exercised     0 7.01  
Weighted Average Exercise Price, Forfeited     11.98 36.31  
Weighted Average Exercise Price, Expired     56.12 83.49  
Weighted Average Exercise Price, Outstanding Balance     20.58 $ 31.16 $ 44.00
Weighted Average Exercise Price, Vested and expected to vest     20.58    
Weighted Average Exercise Price, Exercisable     $ 1.25    
Weighted-Average Remaining Contractual Life, Outstanding (in years)     7 years 7 months 6 days 8 years 3 months 18 days 8 years 7 months 6 days
Weighted-Average Remaining Contractual Life, Vested and expected to vest (in years)     7 years 7 months 6 days    
Weighted-Average Remaining Contractual Life, Exercisable (in years)     5 years 3 months 18 days    
Aggregate Intrinsic Value, Outstanding   $ 52,200 $ 3,733,900 $ 66,329,800  
Aggregate Intrinsic Value, Exercised     0 1,125,600  
Aggregate Intrinsic Value, Outstanding     52,200 $ 3,733,900 $ 66,329,800
Aggregate Intrinsic Value, Vested and expected to vest     52,200    
Aggregate Intrinsic Value, Exercisable     $ 52,200