XML 35 R51.htm IDEA: XBRL DOCUMENT v3.19.3
Stockholders' Equity - Additional Information (Details 1)
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended 28 Months Ended
Oct. 22, 2018
USD ($)
$ / shares
shares
Apr. 19, 2018
shares
Feb. 06, 2018
USD ($)
$ / shares
shares
Jan. 17, 2018
shares
Jul. 18, 2017
USD ($)
$ / shares
shares
Sep. 13, 2016
USD ($)
Sep. 13, 2016
USD ($)
Oct. 31, 2017
USD ($)
shares
Sep. 30, 2017
USD ($)
shares
Jul. 31, 2017
USD ($)
$ / shares
shares
Mar. 31, 2019
USD ($)
shares
Jun. 30, 2018
USD ($)
shares
Mar. 31, 2018
USD ($)
shares
Jun. 30, 2019
USD ($)
shares
Jun. 30, 2018
USD ($)
Dec. 31, 2018
USD ($)
shares
Dec. 31, 2017
USD ($)
shares
Dec. 31, 2018
USD ($)
shares
Jan. 16, 2018
shares
Jun. 30, 2017
$ / shares
shares
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Common stock, shares authorized | shares       50,000,000                   50,000,000   50,000,000 50,000,000 50,000,000 200,000,000  
Common stock, shares issued | shares                           17,645,720   8,645,720 2,265,320 8,645,720    
Common stock, shares outstanding | shares                           17,645,720   8,645,720 2,265,320 8,645,720    
Preferred stock, shares authorized | shares                           10,000,000   10,000,000 10,000,000 10,000,000    
Preferred stock, shares issued | shares                           0   0 0 0    
Preferred stock, shares outstanding | shares                           0   0 0 0    
Proceeds from issuance of common stock, net of issuance costs | $                           $ 4,782,509 $ 192,320 $ 597,743 $ 3,808,836      
Net proceeds from sale of common stock and warrants | $                           0 $ 10,728,131 $ 13,530,401 8,754,882      
Stock split                               On January 17, 2018, the Company filed an amendment to its Amended and Restated Certificate of Incorporation to effect a reverse stock split of the issued and outstanding shares of common stock, at a ratio of one share for twenty-five shares, and to reduce the authorized shares of common stock from 200,000,000 to 50,000,000 shares. All share amounts and per share prices in this Annual Report have been adjusted to reflect the reverse stock split.        
Reverse stock split conversion ratio       0.04                                
Share-based compensation, tax benefit from compensation expense | $                           $ 0   $ 0        
Employee service share-based compensation, non-vested awards, compensation cost not yet recognized, total | $                               $ 500,000   $ 500,000    
Employee service share-based compensation, non-vested awards, compensation cost not yet recognized, period for recognition                               7 years 7 months 6 days        
Share-based compensation arrangement by share-based payment award, options, vested in period, fair value | $                               $ 93,092,100,000 208,684,300,000      
Restricted Stock Units R S U [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Employee service share-based compensation, non-vested awards, compensation cost not yet recognized, period for recognition                               11 months 1 day        
Employee service share-based compensation, non-vested awards, compensation cost not yet recognized, total | $                               $ 900,000,000   $ 900,000,000    
Two Thousand Fifteen Plan [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Share-based compensation arrangement by share-based payment award, number of shares authorized | shares                           54,200   54,200   54,200    
Share-based compensation arrangement by share-based payment award, description                           the number of shares that have been authorized for issuance under the 2015 Plan will be automatically increased on the first day of each fiscal year beginning on January 1, 2016 and ending on (and including) January 1, 2025, in an amount equal to the lesser of (1) 4% of the outstanding shares of common stock on the last day of the immediately preceding fiscal year, or (2) another lesser amount determined by the Company’s Board of Directors.   the number of shares that have been authorized for issuance under the 2015 Plan will be automatically increased on the first day of each fiscal year beginning on January 1, 2016 and ending on (and including) January 1, 2025, in an amount equal to the lesser of (1) 4% of the outstanding shares of common stock on the last day of the immediately preceding fiscal year, or (2) another lesser amount determined by the Company’s Board of Directors.        
Share-based compensation arrangement by share-based payment award, number of shares available for grant | shares                           84,412   50,863   50,863    
Share-based compensation arrangement by share-based payment award, common stock percentage                           4.00%   4.00%        
February Two Thousand Eighteen Public Offering [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Stock issued during period, shares, new issues | shares     2,841,152                                  
Shares issued, price per share | $ / shares     $ 3.25                                  
Gross proceeds from sale of common stock and warrants | $     $ 12,000,000                                  
Net proceeds from sale of common stock and warrants | $     $ 10,700,000                                  
Sale of stock, description of transaction                           Each unit included one share of common stock and one common warrant to purchase 0.5 share of common stock at an exercise price of $3.25 per share. Each pre-funded unit included one pre-funded warrant to purchase one share of common stock for an exercise price of $0.01 per share, and one common warrant to purchase 0.5 share of common stock at an exercise price of $3.25 per share.   Each unit included one share of common stock and one common warrant to purchase 0.5 share of common stock at an exercise price of $3.25 per share. Each pre-funded unit included one pre-funded warrant to purchase one share of common stock for an exercise price of $0.01 per share, and one common warrant to purchase 0.5 share of common stock at an exercise price of $3.25 per share.        
Class of warrant or right, number of securities called by each warrant or right | shares     0.5                                  
Class of warrant or right, exercise price of warrants or rights | $ / shares     $ 3.25                                  
Warrants exercisable period     5 years                                  
February Two Thousand Eighteen Public Offering [Member] | Placement Agent [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Class of warrant or right, exercise price of warrants or rights | $ / shares     $ 4.0625                                  
Warrants exercisable period     5 years                                  
July Two Thousand Seventeen Public Offering [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Stock issued during period, shares, new issues | shares         18,164,195                              
Shares issued, price per share | $ / shares         $ 0.40                              
Gross proceeds from sale of common stock and warrants | $         $ 1,000,000                              
Net proceeds from sale of common stock and warrants | $         $ 8,800,000                              
Sale of stock, description of transaction                               Each unit included one twenty-fifth of a share of common stock and one common warrant to purchase one twenty-fifth of a share of common stock at an exercise price of $10.625 per share. Each pre-funded unit included one pre-funded warrant to purchase one twenty-fifth of a share of common stock for an exercise price of $0.25 per share, and one common warrant to purchase one twenty-fifth of a share of common stock at an exercise price of $10.625 per share.        
Class of warrant or right, number of securities called by each warrant or right | shares         0.04                              
Class of warrant or right, exercise price of warrants or rights | $ / shares         $ 10.625                              
Warrants exercisable period         5 years                              
July Two Thousand Seventeen Public Offering [Member] | Bridge Financing Notes [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Repayment of principal amount of outstanding debt | $         $ 100,000         $ 100,000                    
Repayments of accrued interest on outstanding debt | $         $ 643,800,000                              
July Two Thousand Seventeen Public Offering [Member] | Placement Agent [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Class of warrant or right, exercise price of warrants or rights | $ / shares         $ 12.50                              
Warrants exercisable period         5 years                              
At The Market Offering [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Stock issued during period, value, new issues | $             $ 115         $ 192,320       $ 597,743 $ 3,808,836      
Stock issued during period, shares, new issues | shares                               318,236 227,216 690,247    
At The Market Offering [Member] | Cowen And Company Limited Liability Company [Member] | Sales Agreement [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Aggregate gross proceeds from issuance of common stock | $                               $ 9,400,000   $ 9,400,000    
Stock issued during period, value, new issues | $           $ 11,500,000 $ 11,500,000                          
Maximum commission percentage on gross proceeds             3.00%                          
Aggregate net proceeds from issuance of common stock | $                               8,800,000   $ 8,800,000    
Proceeds from issuance of common stock, net of issuance costs | $                               600,000        
Gross proceeds from sale of common stock | $                               600,000        
At The Market Offering [Member] | Cowen And Company Limited Liability Company [Member] | Sales Agreement [Member] | Maximum [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Aggregate gross proceeds from issuance of common stock | $           $ 25,000,000 $ 2,500,000,000,000                          
Public Placement [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Stock issued during period, value, new issues | $                     $ 4,782,509 6,731 $ 10,721,400     $ 13,530,401 $ 8,823,242      
Stock issued during period, shares, new issues | shares                               5,912,307 1,000,000      
Common Stock [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Stock issued during period, value, new issues | $                               $ 3,182 $ 2,272      
Stock issued during period, shares, new issues | shares                               318,236 227,216 690,247    
Common Stock [Member] | Premerger Dispute Settlement [Member] | Advandx [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Stock issued during period, value, new issues | $                 $ 11,000,000,000                      
Stock issued during period, shares, new issues | shares                 15,843                      
Common Stock [Member] | Vendor Consulting Services [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Stock issued during period, value, new issues | $               $ 2,324,500,000                        
Stock issued during period, shares, new issues | shares               2,898                        
Common Stock [Member] | October Two Thousand Eighteen Public Offering [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Stock issued during period, value, new issues | $                               $ 3,182 $ 2,272      
Stock issued during period, shares, new issues | shares 2,220,000                             318,236 227,216 690,247    
Proceeds from issuance of common stock, net of issuance costs | $ $ 2,800,000                                      
Gross proceeds from sale of common stock | $ $ 3,200,000                                      
Shares issued, price per share | $ / shares $ 1.45                                      
Common Stock [Member] | February Two Thousand Eighteen Public Offering [Member] | Placement Agent [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Class of warrant or right, number of securities called by warrants or rights | shares     184,615                                  
Common Stock [Member] | July Two Thousand Seventeen Public Offering [Member] | Placement Agent [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Class of warrant or right, number of securities called by warrants or rights | shares         50,000                              
Common Stock [Member] | At The Market Offering [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Stock issued during period, value, new issues | $             115         $ 1,040       $ 597,743 $ 3,808,836      
Stock issued during period, shares, new issues | shares                       104,043       318,236 227,216 690,247    
Common Stock [Member] | At The Market Offering [Member] | Cowen And Company Limited Liability Company [Member] | Sales Agreement [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Stock issued during period, shares, new issues | shares                               318,236   690,247    
Common Stock [Member] | Public Placement [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Stock issued during period, value, new issues | $                     $ 90,000 $ 6,731 $ 30,192     $ 3,182 $ 2,272      
Stock issued during period, shares, new issues | shares                     9,000,000 673,077 3,019,230     318,236 227,216 690,247    
Pre Funded Warrant [Member] | February Two Thousand Eighteen Public Offering [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Class of warrant or right, exercise price of warrants or rights | $ / shares     $ 0.01                                  
Warrants exercised | shares   851,155                           851,155        
Pre Funded Warrant [Member] | July Two Thousand Seventeen Public Offering [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Class of warrant or right, number of securities called by each warrant or right | shares         0.04                              
Class of warrant or right, exercise price of warrants or rights | $ / shares         $ 0.25                              
Prefunded Units [Member] | February Two Thousand Eighteen Public Offering [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Stock issued during period, shares, new issues | shares     851,155                                  
Shares issued, price per share | $ / shares     $ 3.24                                  
Prefunded Units [Member] | July Two Thousand Seventeen Public Offering [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Stock issued during period, shares, new issues | shares         6,835,805                              
Shares issued, price per share | $ / shares         $ 0.39                              
Additional Paid In Capital [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Stock issued during period, value, new issues | $                               $ 594,561 $ 3,806,564      
Additional Paid In Capital [Member] | At The Market Offering [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Stock issued during period, value, new issues | $             $ 115         $ 191,280       $ 597,743 $ 3,808,836      
Stock issued during period, shares, new issues | shares                               318,236 227,216 690,247    
Additional Paid In Capital [Member] | Public Placement [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Stock issued during period, value, new issues | $                     $ 4,692,509   $ 10,691,208     $ 594,561 $ 3,806,564      
Stock issued during period, shares, new issues | shares                               5,912,307 1,000,000      
Warrant [Member] | Bridge Financing Notes [Member] | Note Purchase Agreement [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Class of warrant or right, exercise price of warrants or rights | $ / shares                   $ 17.25                    
Class of warrant or right, number of securities called by warrants or rights | shares                   6,350                    
Stock Purchase Warrants [Member] | Bridge Financing Notes [Member] | Note Purchase Agreement [Member]                                        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                        
Class of warrant or right, exercise price of warrants or rights | $ / shares                                       $ 19.50
Class of warrant or right, number of securities called by warrants or rights | shares                                       5,634