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Consolidated Statements of Operations and Comprehensive Loss - USD ($)
3 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Sep. 30, 2017
Sep. 30, 2016
Dec. 31, 2016
Dec. 31, 2015
Revenue            
Product sales $ 729,742 $ 730,325 $ 2,145,371 $ 2,705,690 $ 3,524,178 $ 2,701,142
Laboratory services 9,070 23,036 41,025 182,130 228,904 120,476
Collaboration revenue 6,302 6,302 33,699 131,302 272,603 336,102
Total revenue 745,114 759,663 2,220,095 3,019,122 4,025,685 3,157,720
Operating expenses            
Cost of products sold 448,407 400,001 1,266,148 1,269,990 1,658,571 1,179,771
Cost of services 49,119 51,802 228,115 528,733 631,333 367,802
Research and development 1,513,157 2,178,818 5,397,906 6,278,829 8,613,236 6,002,941
General and administrative 1,600,577 1,639,996 5,319,811 4,955,096 6,602,608 5,834,642
Sales and marketing 330,305 1,294,640 2,345,293 4,282,628 5,529,274 4,305,444
Transaction expenses         0 526,283
Total operating expenses 3,941,565 5,565,257 14,557,273 17,315,276 23,035,022 18,216,883
Operating loss (3,196,451) (4,805,594) (12,337,178) (14,296,154) (19,009,337) (15,059,163)
Other expense            
Interest and other (expense)/income         (5,967) 26,657
Other (expense)/income (87,292) 623 (87,270) (3,078)    
Interest expense (90,317) (41,423) (173,974) (109,806) (143,347) (1,801,320)
Foreign currency transaction gains/(losses) 8,018 (1,269) 19,636 2,293 (8,102) 0
Change in fair value of derivative financial instruments 97,395 0 124,139 0 0 (647,342)
Total other expense (72,196) (42,069) (117,469) (110,591) (157,416) (2,422,005)
Loss before income taxes (3,268,647) (4,847,663) (12,454,647) (14,406,745) (19,166,753) (17,481,168)
Provision for income taxes 0 0 0 0 0 (129,095)
Net loss (3,268,647) (4,847,663) (12,454,647) (14,406,745) (19,166,753) (17,352,073)
Preferred stock dividends and beneficial conversion 0 0 0 (332,550) (332,500) (243,762)
Net loss available to common stockholders $ (3,268,647) $ (4,847,663) $ (12,454,647) $ (14,739,295) $ (19,499,303) $ (17,595,835)
Net loss per common share - basic and diluted $ (1.75) $ (5.75) $ (9.25) $ (23.00) $ (27.50) $ (55.00)
Weighted average shares outstanding - basic and diluted 1,883,136 837,548 1,358,259 641,121 706,702 319,239
Net loss $ (3,268,647) $ (4,847,663) $ (12,454,647) $ (14,406,745) $ (19,166,753) $ (17,352,073)
Other comprehensive income/(loss) - foreign currency translation (6,234) 672 (13,825) 1,059 7,235 (1,059)
Comprehensive loss $ (3,274,881) $ (4,846,991) $ (12,468,472) $ (14,405,686) $ (19,159,518) $ (17,353,132)