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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2016
Income Tax Disclosure [Abstract]  
Deferred tax assets and liabilities
    December 31,  
    2016     2015  
Deferred tax assets:            
NOL carryforward   $ 60,357,220     $ 38,797,762  
R&E credit carryforward     2,559,479       1,994,478  
Share-based compensation     448,534       383,153  
Inventory reserve     269,708       226,299  
Depreciation     117,629       313,714  
Accruals and other     333,126       495,640  
Total deferred tax assets     64,085,696       42,211,046  
Valuation allowance     (63,520,548 )     (41,554,045 )
Deferred tax liabilities:                
Intangible assets     (565,148 )     (657,001 )
Fixed assets            
Net deferred tax liability   $     $  
Expected income tax provision (benefit) from applying federal statutory tax rates to the pre-tax loss and actual income tax provision (benefit)
    2016     2015  
Federal income tax benefit at statutory rates     34.0 %     34.0 %
State income tax benefit, net of Federal benefit     6.5 %     3.3 %
Change in valuation allowance     (37.3 )%     (32.1 )%
Change in state tax rates and other     (3.2 )%     (4.5 )%
      0.0 %     0.7 %