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Stockholders' Equity (Details Textual 1) - USD ($)
1 Months Ended 2 Months Ended 3 Months Ended 12 Months Ended
Jun. 27, 2016
May 08, 2015
Jul. 31, 2016
Jun. 30, 2016
Mar. 31, 2017
Mar. 31, 2016
Dec. 31, 2016
Dec. 31, 2015
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                
Common stock, shares authorized         200,000,000   200,000,000 200,000,000
Common stock, shares issued         27,377,490   25,304,270 12,547,684
Common stock, shares outstanding         27,377,490   25,304,270 12,547,684
Preferred stock, shares authorized         10,000,000   10,000,000 10,000,000
Preferred stock, shares issued         0   0 0
Preferred stock, shares outstanding         0   0 0
Proceeds from issuance of common stock, net of issuance costs         $ 2,122,861 $ 0 $ 4,405,973 $ 17,366,620
Proceeds from issuance of private placement net $ 9,500,000     $ 9,500,000     9,460,749 0
Convertible preferred stock, beneficial conversion feature recognized as deemed dividend     $ 332,550   33,255,000,000      
Proceeds from issuance of units under initial public offering gross   $ 17,100,000            
Proceeds from issuance of units under initial public offering net   $ 12,100,000            
Stock and warrants issued during period shares initial public offering purchase price per unit   $ 6.00            
Share-based compensation, tax benefit from compensation expense         $ 0   0  
Employee service share-based compensation, non-vested awards, compensation cost not yet recognized, total             $ 2,200,000  
Employee service share-based compensation, non-vested awards, compensation cost not yet recognized, period for recognition             1 year 2 months 1 day  
Share-based compensation arrangement by share-based payment award, options, vested in period, fair value             $ 1,088,978 $ 1,140,079
Share-based compensation arrangement by share-based payment award, options, grants in period, gross         723,600   1,463,650 1,961,637