Stockholders' Equity (Tables)

3 Months Ended

12 Months Ended

Mar. 31, 2017

Dec. 31, 2016

Stockholders' Equity Note [Abstract]

Schedule of allocation of share-based compensation expense

For the three months ended March 31, 2017 and 2016, the Company recognized stock compensation expense as follows:

	Three Months Ended March 31,
	2017		2016
Cost of services	$	1,823	$	4,312
Research and development		57,778		62,218
General and administrative		152,476		172,103
Sales and marketing		33,328		22,864
	$	245,405	$	261,497

For the years ended December 31, 2016 and 2015, the Company recognized stock compensation expense as follows:

	Year Ended December 31,
	2016		2015
Cost of services	$	6,003	$	—
Research and development		236,341		240,739
General and administrative		599,550		619,899
Sales and marketing		103,567		584,450
	$	945,461	$	1,445,088

Schedule of share-based compensation, options granted

A summary of the status of options granted is presented below as of and for the years ended December 31, 2016 and 2015:

	Number of Options			Weighted- Average Exercise Price		Weighted- Average Remaining Contractual Life (in years)		Aggregate Intrinsic Value
Outstanding at January 1, 2015		404,272					9.3	$	—
Granted		1,961,637		$	2.68
Exercised		(11,472	)	$	0.20			$	19,519
Forfeited		(193,657	)	$	0.55
Outstanding at December 31, 2015		2,160,780		$	2.60		9.1	$	1,575,646
Granted		1,463,650		$	1.41
Exercised		(66,502	)	$	0.36			$	79,406
Forfeited		(571,687	)	$	3.99
Expired		(8,581	)	$	8.49
Outstanding at December 31, 2016		2,977,660		$	1.76		8.6	$	663,298
Vested and expected to vest		2,977,660		$	1.76		8.6	$	663,298
Exercisable at December 31, 2016		1,098,504		$	0.22		8.0	$	421,621

Schedule of share-based payment award, Stock Options granted, fair value

The fair value of each option grant was estimated at the date of grant using the Black-Scholes option pricing model based on the assumptions below:

	Year Ended December 31,
	2016		2015
Annual dividend		—		—
Expected life (in years)	5.25 - 6.25		5.5 - 6.25
Risk free interest rate	1.2 - 2.2%		1.5 - 1.9%
Expected volatility	42.0 - 49.8%		47.7 - 65.0%

Schedule of warrants to purchase shares of common stock

Stock purchase warrants

At March 31, 2017 and December 31, 2016, the following warrants to purchase shares of common stock were outstanding:

				Outstanding at
Issuance	Exercise Price		Expiration	March 31, 2017		December 31, 2016
August 2007	$	7.91	August 2017		8,921		8,921
March 2008	$	790.54	March 2018		46		46
November 2009	$	7.91	November 2019		6,674		6,674
January 2010	$	7.91	January 2020		6,674		6,674
March 2010	$	7.91	March 2020		1,277		1,277
November 2011	$	7.91	November 2021		5,213		5,213
December 2011	$	7.91	December 2021		664		664
March 2012	$	109.90	March 2019		4,125		4,125
February 2015	$	6.60	February 2025		225,011		225,011
May 2015	$	6.60	May 2020		3,457,750		3,457,750
May 2016	$	1.31	May 2021		4,739,348		4,739,348
June 2016	$	1.31	May 2021		2,050,821		2,050,821
					10,506,524		10,506,524

At December 31, 2016 and 2015, the following warrants to purchase shares of common stock were outstanding:

				Outstanding at December 31,
Issuance	Exercise Price		Expiration	2016		2015
August 2007	$	7.91	August 2017		8,921		8,921
March 2008	$	790.54	March 2018		46		46
November 2009	$	7.91	November 2019		6,674		6,674
January 2010	$	7.91	January 2020		6,674		6,674
March 2010	$	7.91	March 2020		1,277		1,277
November 2011	$	7.91	November 2021		5,213		5,213
December 2011	$	7.91	December 2021		664		664
March 2012	$	109.90	March 2019		4,125		4,125
February 2015	$	6.60	February 2025		225,011		225,011
May 2015	$	6.60	May 2020		3,457,750		3,457,750
May 2016	$	1.31	May 2021		4,739,348		—
June 2016	$	1.31	May 2021		2,050,821		—
					10,506,524		3,716,355