X0306 4 2014-02-14 0000005768 AMERICAN SCIENCE & ENGINEERING, INC. ASEI 0001293565 Callerame Joseph AMERICAN SCIENCE AND ENGINEERING, INC. 829 MIDDLESEX TURNPIKE BILLERICA MA 01821 0 1 0 0 SVP Common Stock 2014-02-14 4 M 0 8629 39.06 A 21943 D Common Stock 2014-02-14 4 S 0 8629 65.02 D 13314 D Common Stock 475 I By 401(k) Plan Employee Stock Option (Right to Buy) 39.06 2014-02-14 4 M 0 8629 0 D 2014-12-02 Common Stock 8629 0 D The price reported is a weighted average price. These stock options were sold in multiple transactions at prices ranging from a low of $65.00 to a high of $65.36 for an average of $65.019. The reporting person undertakes to provide to American Science and Engineering, Inc., any security holder of American Science and Engineering, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote to this Form 4. Shares of AS&E common stock acquired under the AS&E 401(k) Plan. The information in this report is based on a plan statement dated as of February 18, 2014. The option vested in three equal installments on December 2, 2005, 2006 and 2007. John B. De Luca, attorney-in-fact 2014-02-19