Stock-Based Compensation (Tables)

6 Months Ended

Jun. 30, 2022

Share-Based Payment Arrangement [Abstract]

Schedule of stock option activity

	Options			Weighted Average Exercise Price
Outstanding at January 1, 2022		4,429,906		$	7.89
Granted		350,078		$	2.99
Exercised		-		$	-
Cancelled (forfeited)		(67,325	)	$	15.09
Cancelled (expired)		(27,025	)	$	13.64
Outstanding at June 30, 2022		4,685,634		$	7.39

Schedule of options granted using the Black-Scholes options pricing model

	Six Months Ended
	June 30, 2022
Exercise price	2.99
Market value	2.99
Expected term	6 years
Expected volatility	104%
Risk-free interest rate	1.59%
Expected dividend yield	-%

Schedule of stock-based compensation expense

	Three Months Ended June 30,				Six Months Ended June 30,
	2022		2021		2022		2021
General and administrative	$	1,341	$	1,407	$	2,635	$	1,771
Research and development		294		464		543		610
Total stock-based compensation	$	1,635	$	1,871	$	3,178	$	2,381