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Organization and Description of Business (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
Nov. 12, 2019
Jun. 04, 2018
Mar. 12, 2018
Dec. 31, 2019
Jun. 28, 2019
Apr. 23, 2019
May 31, 2019
Aug. 31, 2018
Dec. 31, 2019
Dec. 31, 2018
Accumulated deficit       $ 284,895         $ 284,895 $ 274,601
Total liabilities       14,841         14,841 9,480
Working capital deficit       13,100         13,100  
Proceeds from issuance of exercise of stock options                 325
Proceeds from issuance of common stock   $ 200 $ 1,100 200         185 2,781
Proceeds from advance notes               $ 900 $ 2,050 $ 925
Percentage of high concentration in patients                 20.00%  
Lincoln Park Capital Purchase Agreement [Member]                    
Proceeds from issuance of common stock       $ 186            
2019 Convertible Notes Payable [Member]                    
Proceeds from advance notes           $ 1,300        
June Bridge Notes [Member]                    
Proceeds from advance notes         $ 1,700          
Bridge Loan [Member]                    
Proceeds from advance notes $ 350                  
Chairman and Chief Executive Officer and two other members of our Board of Directors [Member]                    
Proceeds from issuance of exercise of stock options             $ 324