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Stockholders' Equity (Stock Option Activity) (Details) - USD ($)
$ / shares in Units, $ in Thousands
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Number of Shares    
Balance at the beginning of the period (in shares) 2,448,383 1,835,835
Options granted (in shares) 13,575,038 765,000
Options forfeited (in shares) (572,935) (152,365)
Options expired (in shares) (41,129) (87)
Balance at the end of the period (in shares) 15,409,357 2,448,383
Options vested and expected to vest at the end of the period (in shares) 15,356,965  
Options exercisable (in shares) 10,283,026  
Weighted-Average Exercise Price (Per Share)    
Balance at the beginning of the period (in dollars per share) [1] $ 4.15 $ 19.29
Options granted (in dollars per share) [1] 0.66 3.38
Options forfeited (in dollars per share) [1] 3.20 5.86
Options expired (in dollars per share) [1] 37.82 18.38
Balance at the ending of the period (in dollars per share) [1] 0.95 $ 4.15
Options vested and expected to vest at the end of the period (in dollars per share) [1] 0.95  
Options exercisable (in dollars per share) [1] $ 1.01  
Weighted-Average Remaining Contractual Term (in years)    
Balance at the end of the period 9 years  
Options vested and expected to vest at the end of the period 9 years  
Options exercisable 9 years  
Aggregate Intrinsic Value (in thousands)    
Balance at the end of the period [2] $ 576  
Options vested and expected to vest at the end of the period [2] 574  
Options exercisable [2] $ 379  
[1] The weighted average price per share is determined using exercise price per share for stock options.
[2] The aggregate intrinsic value is calculated as the difference between the exercise price of the option and the fair value of the Company's common stock for in-the-money options at December 31, 2018.