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Savant Arrangements (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 12 Months Ended
Jul. 10, 2017
May 26, 2017
Dec. 31, 2018
Dec. 31, 2017
Jun. 30, 2016
Number of shares called by warrant     331,193    
Milestone payments and certain other contingent payments     $ 2,000 $ 2,000  
Research and development $ 1,000 $ 1,000 $ 2,219 $ 11,165  
Savant Neglected Diseases, LLC [Member]          
Number of shares called by warrant         200,000
Exercise price of warrant         $ 2.25