Organization and Description of Business (Details) $ in Thousands			1 Months Ended		3 Months Ended	12 Months Ended
	Jun. 04, 2018 USD ($) shares	Mar. 12, 2018 USD ($) shares	Sep. 19, 2018 USD ($)	Feb. 27, 2018 USD ($) shares	Aug. 31, 2018 USD ($)	Dec. 31, 2018 USD ($) item shares	Dec. 31, 2017 USD ($) shares
Accumulated deficit						$ 274,601	$ 262,597
Number of product candidates approved for sale | item						0
Total liabilities						$ 9,480	$ 26,006
Working capital deficit						$ 7,000
Common share issued | shares	400,000	2,445,557		91,815,517		109,872,526	14,946,712
Cash proceeds from issuance of common stock				$ 1,500
Proceeds from issuance of common stock	$ 200	$ 1,100				$ 2,781
Proceeds from advance notes					$ 900	$ 925
Convertible Promissory Note [Member]
Proceeds from advance notes			$ 2,500