Organization and Description of Business (Details) $ in Thousands	3 Months Ended
	Mar. 31, 2016 USD ($) item	Dec. 31, 2015 USD ($)
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Accumulated deficit	$ 219,017	$ 213,591
Number of product candidates approved for sale | item	0
Total liabilities	$ 8,185	$ 5,414