Nature of Operations (Details) $ in Thousands	9 Months Ended
	Sep. 30, 2015 USD ($) item	Dec. 31, 2014 USD ($)
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Accumulated deficit	$ 200,475	$ 178,213
Liabilities	$ 12,603	$ 18,364
Number of product candidates approved for sale | item	0