Stockholders' Equity (Tables)

9 Months Ended

Sep. 30, 2015

Stockholders' Equity Note [Abstract]

Summary of stock option activity

				Weighted
				Average
				Exercise
	Options			Price
Outstanding at December 31, 2014		334,686			$	34.00
Granted		296,045				3.59
Exercised		—				—
Cancelled (forfeited)		(96,158	)			24.55
Cancelled (expired)		(7,453	)			18.22
Outstanding at September 30, 2015		527,120			$	18.84

Schedule of fair value assumptions

	Three Months Ended			Nine Months Ended
Exercise price	$	3.23		$	3.59
Market value	$	3.23		$	3.59
Risk-free rate		1.62			1.61
Expected term		5.30			5.81
Expected volatility		69	%		70	%
Dividend yield		-			-

Schedule of total stock-based compensation expense recognized

	Three Months					Nine Months
	Ended September 30,					Ended September 30,
(in thousands)		2015		2014			2015		2014
General and administrative		$	137	$	282		$	466	$	755
Research and development			134		184			447		729
		$	271	$	466		$	913	$	1,484