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Revenue Recognized under Sanofi Agreement (Detail) (USD $)
In Thousands, unless otherwise specified
3 Months Ended 9 Months Ended
Sep. 30, 2013
Sep. 30, 2012
Sep. 30, 2013
Sep. 30, 2012
Contract revenue:        
Amortization of upfront fees       $ 5,630
Reimbursement for development-related activities 9 69 40 450
Total contract revenue $ 9 $ 69 $ 40 $ 6,080