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Property And Equipment (Detail) (USD $)
In Thousands, unless otherwise specified
Dec. 31, 2012
Dec. 31, 2011
Property, Plant and Equipment [Line Items]    
Property and equipment, gross $ 3,174 $ 3,211
Accumulated depreciation and amortization (2,944) (2,784)
Property and equipment, net 230 427
Laboratory equipment
   
Property, Plant and Equipment [Line Items]    
Property and equipment, gross 1,453 1,508
Computer equipment and software
   
Property, Plant and Equipment [Line Items]    
Property and equipment, gross 435 421
Leasehold improvements, furniture and fixtures
   
Property, Plant and Equipment [Line Items]    
Property and equipment, gross $ 1,286 $ 1,282