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Outstanding Potentially Dilutive Securities Excluded From Computations of Diluted Net Loss Per Common Share (Detail)
12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Antidilutive securities excluded from computation of earnings per share, amount 13,432,154 11,921,359 11,831,210
Convertible preferred stock
     
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Antidilutive securities excluded from computation of earnings per share, amount 12,329,330 10,657,030 10,657,030
Unvested common stock
     
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Antidilutive securities excluded from computation of earnings per share, amount   139,033 172,402
Warrants to purchase preferred stock
     
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Antidilutive securities excluded from computation of earnings per share, amount 72,029 38,997 38,997
Options to purchase common stock
     
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Antidilutive securities excluded from computation of earnings per share, amount 1,030,795 1,086,299 962,781