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Property And Equipment (Detail) (USD $)
In Thousands, unless otherwise specified
Sep. 30, 2012
Dec. 31, 2011
Dec. 31, 2010
Property, Plant and Equipment [Line Items]      
Property and equipment, gross $ 3,157 $ 3,211 $ 2,747
Accumulated depreciation and amortization (2,901) (2,784) (2,300)
Property and equipment, net 256 427 447
Laboratory equipment
     
Property, Plant and Equipment [Line Items]      
Property and equipment, gross 1,446 1,508 1,259
Computer equipment and software
     
Property, Plant and Equipment [Line Items]      
Property and equipment, gross 425 421 401
Leasehold improvements, furniture and fixtures
     
Property, Plant and Equipment [Line Items]      
Property and equipment, gross $ 1,286 $ 1,282 $ 1,087