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Sanofi (Details) (Sanofi [Member], USD $)
In Millions, unless otherwise specified
6 Months Ended
Jun. 30, 2014
Jul. 31, 2014
Subsequent Event [Member]
Research and Development Collaboration and License Agreements    
Initial upfront non-refundable payment $ 35  
Additional non-refundable payment 5  
Development, regulatory and commercial contingent payments 250  
Maximum days to participate in development and promotion of products 90 days  
Maximum amount of royalties to be payable   40
Percentage of sub-license payments to be shared   10.00%
Maximum amount of sub-license payments to be shared   $ 40