X0306 4 2022-06-02 0 0001192448 GLAUKOS Corp GKOS 0001293171 Kliman Gilbert H C/O GLAUKOS CORPORATION 229 AVENIDA FABRICANTE SAN CLEMENTE CA 92672 1 0 0 0 Common Stock 2022-06-02 4 A 0 4364 0.00 A 8260 D Common Stock 13965 I By InterWest Venture Management Company Common Stock 333917 I InterWest Partners X, LP Common Stock 3362 I By InterWest Partners IX, LP Represents a grant of restricted stock units that vest in full on the one-year anniversary of the grant date and are payable in an equivalent number of shares of the Issuer's common stock. Includes 6,746 restricted stock units that have not yet vested or been delivered to the Reporting Person. Consists of shares owned by InterWest Venture Management Company ("IVMC"). The Reporting Person is an officer, director and the sole shareholder of IVMC and has sole voting and investment control over the shares held by IVMC. Consists of shares owned by InterWest Partners X, LP ("IP10"). The Reporting Person has shared voting and investment control over shares owned by IP10, and disclaims beneficial ownership of those securities, except to the extent of his pecuniary interest therein. Consists of shares owned by InterWest Partners IX, LP ("IP9"). The Reporting Person is a Managing Director of InterWest Management Partners IX, LLC, the general partner of IP9. The Reporting Person has shared voting and investment control over shares owned by IP9, and disclaims beneficial ownership of those securities, except to the extent of his pecuniary interest therein. Diana Scherer, Attorney-in-Fact 2022-06-06