WARRANTS (Details)	12 Months Ended
	Dec. 31, 2022 $ / shares shares
Warrants to purchase common stock issued and outstanding
Number of Warrants | shares	3,064,877
Weighted average exercise price | $ / shares	$ 8.54
Weighted average life in years	3 years 8 months 8 days
2018 Warrant Exercise price $6.98
Warrants to purchase common stock issued and outstanding
Warrants Issued Year	2018
Number of Warrants | shares	8,483
Warrant Exercise Price | $ / shares	$ 174.53
Expiration date	Jun. 25, 2023
2019 Warrant Exercise price $4.50
Warrants to purchase common stock issued and outstanding
Warrants Issued Year	2019
Number of Warrants | shares	610
Warrant Exercise Price | $ / shares	$ 112.50
Expiration date	Nov. 21, 2024
2020 Series A Warrants Exercise price $2.75
Warrants to purchase common stock issued and outstanding
Warrants Issued Year	2020
Number of Warrants | shares	72,738
Warrant Exercise Price | $ / shares	$ 68.75
Expiration date	Mar. 10, 2025
2020 Placement Agent Warrants Exercise price $3.475
Warrants to purchase common stock issued and outstanding
Warrants Issued Year	2020
Number of Warrants | shares	29,091
Warrant Exercise Price | $ / shares	$ 5.05
Expiration date	Apr. 11, 2028
2020 Series B Warrants Exercise price $ 0.00001
Warrants to purchase common stock issued and outstanding
Warrants Issued Year	2020
Number of Warrants | shares	6,620
Warrant Exercise Price | $ / shares	$ 85.9400
Expiration date	Mar. 05, 2025
2020 Series C Warrants Exercise price $1.62
Warrants to purchase common stock issued and outstanding
Warrants Issued Year	2020
Number of Warrants | shares	510
Warrant Exercise Price | $ / shares	$ 0.00025
2020 Placement Agent Warrants Exercise price $2.1875
Warrants to purchase common stock issued and outstanding
Warrants Issued Year	2020
Number of Warrants | shares	48,163
Warrant Exercise Price | $ / shares	$ 40.50
Expiration date	Oct. 17, 2025
Warrants Outstanding 2020 Sixth [Member]
Warrants to purchase common stock issued and outstanding
Warrants Issued Year	2020
Number of Warrants | shares	19,048
Warrant Exercise Price | $ / shares	$ 5.05
Expiration date	Apr. 11, 2028
Warrants Outstanding 2020 Seventh [Member]
Warrants to purchase common stock issued and outstanding
Number of Warrants | shares	4,461
Warrant Exercise Price | $ / shares	$ 54.6900
Expiration date	Apr. 15, 2025
Warrants Outstanding 2020 Eight [Member]
Warrants to purchase common stock issued and outstanding
Number of Warrants | shares	48,264
Warrant Exercise Price | $ / shares	$ 25.00
Expiration date	Oct. 22, 2025
Warrants Outstanding 2020 Ninth [Member]
Warrants to purchase common stock issued and outstanding
Number of Warrants | shares	293,174
Warrant Exercise Price | $ / shares	$ 20.00
Expiration date	Oct. 27, 2025
Warrants Outstanding 2020 Tenth [Member]
Warrants to purchase common stock issued and outstanding
Warrants Issued Year	2020
Number of Warrants | shares	32,000
Warrant Exercise Price | $ / shares	$ 5.05
Expiration date	Apr. 11, 2028
Warrants Outstanding 2022 One [Member]
Warrants to purchase common stock issued and outstanding
Warrants Issued Year	2022
Number of Warrants | shares	676,000
Warrant Exercise Price | $ / shares	$ 0.00001
Warrants Outstanding 2022 Two [[Member]
Warrants to purchase common stock issued and outstanding
Warrants Issued Year	2022
Number of Warrants | shares	1,714,286
Warrant Exercise Price | $ / shares	$ 5.05
Expiration date	Apr. 11, 2028
Warrants Outstanding 2022 Three [[Member]
Warrants to purchase common stock issued and outstanding
Warrants Issued Year	2022
Number of Warrants | shares	111,429
Warrant Exercise Price | $ / shares	$ 6.56
Expiration date	Oct. 07, 2024
Placement Agent Warrants
Warrants to purchase common stock issued and outstanding
Warrants Issued Year	2020
October 2020 Offering
Warrants to purchase common stock issued and outstanding
Warrants Issued Year	2020