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SHARE-BASED COMPENSATION, STOCK OPTIONS, AND RESTRICTED SECURITIES (Tables)
12 Months Ended
Dec. 31, 2022
SHARE-BASED COMPENSATION, STOCK OPTIONS, AND RESTRICTED SECURITIES  
Summary of stock based compensation classified in the consolidated statements of operations

For the years ended December 31, 2022 and 2021, Stock-based compensation recognized was classified in the consolidated statements of operations as follows:

Year Ended December 31, 

(In thousands)

    

2022

    

2021

Research and development

$

(8)

$

22

General and administrative

167

293

Total

$

159

$

315

Schedule of assumptions used principally in determining the fair value of options granted

December 31, 

December 31, 

 

    

2022

2021

 

Risk-free interest rate

    

3.87%

1.03%

Expected dividend yield

 

0%

0%

Expected term (employee grants)

 

5.71

5.70

Expected volatility

 

126.66%

117.34%

Summary of option activity

Weighted

Weighted

Average

Average

Remaining

Aggregate

Exercise

Contractual

Intrinsic

Options

    

Shares

    

Price

    

Term in Years

    

Value

Outstanding as of December 31, 2021

 

14,582

$

437.78

9.18

$

Granted

 

126,600

$

2.50

Cancelled/Forfeited

(4,613)

$

345.06

Expired

(1)

$

129,750.00

Outstanding as of December 31, 2022

 

136,568

$

36.46

9.72

$

Vested and Exercisable as of December 31, 2022

 

8,268

$

547.95

8.15

$

Vested and expected to vest as of December 31, 2022

 

136,568

$

36.46

9.72

$

Summary of restricted stock unit activity

Weighted-Average

Restricted Securities

    

Number of Grants

    

Grant Date Fair Value

Unvested balance as of December 31, 2021

254

$

387.05

Vested

(200)

$

387.50

Cancelled/Forfeited

(54)

$

385.38

Unvested balance as of December 31, 2022

$